SANTA CLARA — Injuries to multiple defensive backs, particularly free safety Adrian Colbert, could lead the 49ers to deploy their high-priced, Jimmie Ward Contingency Plan.“I could be at corner, at nickel, at dime and at safety. I still really don’t know,” Ward said Thursday as the 49ers (0-1) prepare to host the Detroit Lions (0-1) on Sunday.Colbert missed his second straight day of practice because of a hamstring injury, and that could open the door for Ward to return to free safety, where …
This week’s entry has a little jargon in it, but if you remember what we’ve said about the tRNA synthetase family of proteins (see 05/26/2004, 07/21/2003 and 06/09/2003 headlines), you’ll get it. Paul Schimmel and Karla Ewalt comment in Cell1 on new discoveries by Sampath et al.2 that two of these synthetases fuse together to regulate the inflammation reaction:Aminoacyl tRNA synthetases are ancient proteins that appeared before the split of the tree of life into its three great kingdoms—archae [sic], eukarya, and bacteria. The 20 enzymes—one for each amino acid—catalyze aminoacylation of tRNAs and thereby establish the rules of the genetic code by associating each amino acid with a nucleotide triplet (the anticodon of the tRNA). The transition from the RNA world to the theater of proteins was thus made possible by the development of specific aminoacylation reactions. While the central connection between synthetases and the code has long been recognized, the modern enzymes have surprised us with novel functions beyond aminoacylation. They are key regulators and active components in a wide range of cellular functions from RNA splicing and transcription to apoptosis and angiogenesis…. …. we now see that tRNA synthetases in mammalian cells have more diverse and comprehensive connections to the inflammatory system than was previously appreciated. The diverse functions of these essential enzymes never cease to amaze!1Paul Schimmel and Karla Ewalt, “Translation Silenced by Fused Pair of tRNA Synthetases,” Cell, Volume 119, Issue 2, 15 October 2004, Pages 147-148, doi:10.1016/j.cell.2004.10.001.2Sampath et al., “Noncanonical Function of Glutamyl-Prolyl-tRNA Synthetase Gene-Specific Silencing of Translation,” Cell, Volume 119, Issue 2, 15 October 2004, Pages 195-208, doi:10.1016/j.cell.2004.09.030.To be an evolutionist, you have to take the Crick brainwashing class. This involves repeating the following quote by Francis Crick over and over until it is engraved on the heart with an iron stylus: “Biologists must constantly keep in mind that what they see was not designed, but evolved.”(Visited 10 times, 1 visits today)FacebookTwitterPinterestSave分享0
There’s nothing new about the notion that many people respond to economic uncertainty by trying to live more economically. This week, one research company reaffirmed that notion with a take on the market for energy-efficient products and clean-technology services. Another research firm, meanwhile, has been examining consumers’ thinking behind these green purchases.On Tuesday, Pike Research, based in Boulder, Colorado, announced results of a study, titled “Energy Efficient Homes,” that indicates recovery from the recession will be accompanied by solid growth in three energy efficiency categories: the market for home energy audits, which Pike expects will almost triple in size, from $8.1 billion in 2009 to $23.4 billion, by 2014; the retrofit market, with a 31% increase, to $50.2 billion from $38.3 billion, by 2014; and purchases of Energy Star certified refrigerators and clothes washers, generating $21.9 billion in revenue from 2009 to 2014.“Energy efficiency is stepping into the light after a long period of obscurity,” Pike’s managing director, Clint Wheelock, said in the release. The principal market drivers, he noted, include “increased environmental awareness among consumers, government incentives, utility energy efficiency programs, and new offerings and rebates from product manufacturers.”Getting real with marketingBack in December another green-trends researcher, Knoxville-based Shelton Group, presented a list titled “Six consumer trends to watch for 2010.” The list noted in-house survey results showing that while consumers respond favorably to the prospect of saving money through green behavior, they even more strongly embraced the “don’t waste” motivation to conserve. The trends list also pointed to consumers’ increased disenchantment with energy efficiency measures that don’t live up to expectations created by the marketing – and the need for marketers to better manage expectations. Also, the list notes, the prospect of saving money will play a somewhat lesser a role in motivating consumers to go green than the prospect of increased comfort and convenience.As for climate change, Shelton Group surveys show fewer and fewer people believe that it is happening and is caused by human activity – a consequence, in part, says the company, of Climategate. (Pennsylvania State University climatologist Michael Mann, a Climategate figure and major contributor to the Intergovernmental Panel on Climate Change, was this week cleared of scientific misconduct in three claims against him; a fourth claim is being reviewed separately.)Dissecting consumer motivationOverall, though, the kerfuffle over Climategate and the apparent drop-off in the number of global-warming believers aren’t having the expected effect, according to the researcher’s preliminary reading of data it collected for its 2010 Eco Pulse study of consumer trends in the green sector. “It appears that green purchasing behavior and propensity is actually up,” Shelton Group says in a blog post. “We’ve been advising our clients and our blog readers for years that most folks don’t go green to save the planet, and this is just more data to that effect. We’re seeing comfort and convenience continue to take precedence over the environment, and we’re seeing health and safety concerns continue to gain ground in priority in some categories.”We’ll keep our eyes peeled for a summary of the final report.
zoom Florida-based shipping company Crowley Maritime Corporation has reached milestones in the construction of two new, combination container and Roll/On-Roll/Off (Commitment Class ConRo) ships which are now taking shape at VT Halter Marine shipyard in Pascagoula.Namely, the bow of El Coquí was recently set as the shipbuilder finished constructing the full length of the ship, aligned the main engine, and completed other work required to prepare the vessel for launching in early 2017.The liquefied natural gas (LNG) tanks also have also been installed and build-out of the engine room and main engine are underway on sister ship, Taíno.As part of a USD 500 million investment in the trade between the US mainland and Puerto Rico, the company is building the new vessels that will be powered by LNG. The investment also includes improvements to the company’s terminal in San Juan.Crowley said that the investment in ships and terminal infrastructure is made possible by the Jones Act, which requires that all goods transported by water between US ports be carried on US-flagged ships constructed in the United States.
Recommended for you Turks & Caicos and United States team up for ‘Don’t Pack a Pest’ program Related Items:agriculture dePARTMENT, dogs ordinance, National Animal Traceability and Identification Programme, re-home Facebook Twitter Google+LinkedInPinterestWhatsApp Facebook Twitter Google+LinkedInPinterestWhatsAppProvidenciales, 29 Sept 2015 – The Department of Agriculture through its recently launched Re-Home programme is ensuring that family pets are properly licensed or registered under the Dogs Ordinance. RE-HOME™ is the licensing and registration programme developed for dogs and cats respectively as part of the National Animal Traceability and Identification Programme (NATIP™). The inaugural event took place in South Caicos and the Department says their purpose is to encourage pet owners to microchip, license their dogs and register their cats in order to build a pet identification database, to use the database for animal disease control and to reunite lost pets with their rightful owners.
San Diego County Board of Supervisors host an evening budget meeting KUSI Newsroom June 12, 2019 Posted: June 12, 2019 SAN DIEGO (KUSI) – For the first time in several years, the County Board of Supervisors will hold an evening budget meeting.Supervisor Fletcher was in studio to tell us all why you should attend the meeting and what you can get out of it.On Thursday, June 13 the first evening budget hearing in several years will take place starting at 5:30 p.m. at 1600 Pacific Highway. Based on what we have heard from the community, we are expecting hundreds to attend. KUSI Newsroom, Categories: Local San Diego News, Politics FacebookTwitter