49ers report: Top 5 things we learned Thursday

first_imgSANTA CLARA — Injuries to multiple defensive backs, particularly free safety Adrian Colbert, could lead the 49ers to deploy their high-priced, Jimmie Ward Contingency Plan.“I could be at corner, at nickel, at dime and at safety. I still really don’t know,” Ward said Thursday as the 49ers (0-1) prepare to host the Detroit Lions (0-1) on Sunday.Colbert missed his second straight day of practice because of a hamstring injury, and that could open the door for Ward to return to free safety, where …last_img read more

Stupid Evolution Quote of the Week

first_imgThis week’s entry has a little jargon in it, but if you remember what we’ve said about the tRNA synthetase family of proteins (see 05/26/2004, 07/21/2003 and 06/09/2003 headlines), you’ll get it.  Paul Schimmel and Karla Ewalt comment in Cell1 on new discoveries by Sampath et al.2 that two of these synthetases fuse together to regulate the inflammation reaction:Aminoacyl tRNA synthetases are ancient proteins that appeared before the split of the tree of life into its three great kingdoms—archae [sic], eukarya, and bacteria.  The 20 enzymes—one for each amino acid—catalyze aminoacylation of tRNAs and thereby establish the rules of the genetic code by associating each amino acid with a nucleotide triplet (the anticodon of the tRNA).  The transition from the RNA world to the theater of proteins was thus made possible by the development of specific aminoacylation reactions.  While the central connection between synthetases and the code has long been recognized, the modern enzymes have surprised us with novel functions beyond aminoacylation.  They are key regulators and active components in a wide range of cellular functions from RNA splicing and transcription to apoptosis and angiogenesis….    …. we now see that tRNA synthetases in mammalian cells have more diverse and comprehensive connections to the inflammatory system than was previously appreciated.  The diverse functions of these essential enzymes never cease to amaze!1Paul Schimmel and Karla Ewalt, “Translation Silenced by Fused Pair of tRNA Synthetases,” Cell, Volume 119, Issue 2, 15 October 2004, Pages 147-148, doi:10.1016/j.cell.2004.10.001.2Sampath et al., “Noncanonical Function of Glutamyl-Prolyl-tRNA Synthetase Gene-Specific Silencing of Translation,” Cell, Volume 119, Issue 2, 15 October 2004, Pages 195-208, doi:10.1016/j.cell.2004.09.030.To be an evolutionist, you have to take the Crick brainwashing class.  This involves repeating the following quote by Francis Crick over and over until it is engraved on the heart with an iron stylus: “Biologists must constantly keep in mind that what they see was not designed, but evolved.”(Visited 10 times, 1 visits today)FacebookTwitterPinterestSave分享0last_img read more

Clean Lake 2020 Plan gets unanimous support in Senate

first_imgShare Facebook Twitter Google + LinkedIn Pinterest  1 CommentProposed legislation that helps farmers help water quality passed 33-0 in the Ohio Senate on Wednesday following Ohio Farm Bureau declaring the measure a “Key Vote.”The Clean Lake 2020 Plan, as it is known, is Senate Bill 299 and House Bill 643. The two bills, introduced into the Ohio Senate and Ohio House of Representatives in early May, would invest significant funds to protect Lake Erie water quality.The Senate unanimously passed SB 299, which will now move to the Ohio House of Representatives for their consideration. HB 643 awaits a committee vote to move forward.Key Vote designation indicates that a piece of legislation is particularly important to agriculture and rural Ohio. Once the bill is designated as a Key Vote, votes will be counted in Ohio Farm Bureau’s process for determining which legislators earn the organization’s Friend of Agriculture designation.Farm Bureau members will receive more details on this and other water policy developments in the July/August 2018 Buckeye Farm News.  1 Commentlast_img read more